[HTML][HTML] The effect of spontaneous osteoarthritis on conditioned pain modulation in the canine model

KW Chiu, J Hash, R Meyers, BDX Lascelles - Scientific Reports, 2020 - nature.com
Abstract Endogenous Pain Modulation (EPM) impairment is a significant contributor to
chronic pain. Conditioned pain modulation (CPM) testing assesses EPM function.
Osteoarthritic (OA) dogs are good translational models, but CPM has not been explored. Our
aim was to assess EPM impairment in OA dogs compared to controls using CPM. We
hypothesized that CPM testing would demonstrate EPM impairment in OA dogs compared to
controls. Dogs with stifle/hip OA and demographically-matched controls were recruited. The …
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